10x Genomics is looking for an outstanding Production Specialist to join the Oligonucleotide Manufacturing team to aid in the development and manufacturing of oligonucleotides from synthesis to characterization. This is a unique cross-disciplinary position that will work closely with a variety of groups including Chemistry, Molecular Biology, and Manufacturing Systems Engineering.

Individuals applying for this position must be creative, passionate, detail-oriented self-starters who thrive in a fast-paced environment through actions driven by strategic thinking. In addition, successful candidates will be flexible in changing direction and approaches, excel at managing multiple priorities, succeed in communicating with all levels within the organization, and provide immediate contribution.

What you will be doing:

• Aid in the conception, development, and optimization of robust oligonucleotide manufacturing methods and processes in preparation for transfer to production
• Complete work orders following established Standard Operating Procedures and take detailed information during high throughput manufacturing processes
• Regular activities range from reagent and buffer preparation to automated liquid handling
• Work with flammable and halogenated solvents following safety protocols
• Operate common and specialized lab equipment (e.g. centrifuges, pH/conductivity meter, incubators, spectrometers, HPLC, liquid handling robots, etc.)
• Leverage new protocols and implement into a rapidly scaling manufacturing pipeline
• Work with research scientists to optimize manufacturing processes and generate experimental data.
• Draft/revise SOPs and Work Instructions for new manufacturing processes
• Installation and verification of equipment, documenting processes, and training operators
• Verifying that the manufactured products output meets all predetermined requirements
• Independently troubleshooting processes and escalate issues as appropriate
• Work independently and in a team to complete daily tasks

Minimum Requirements:

• BS or MS in Chemistry, Biochemistry, Chemical Engineering, or related field
• At least 6 years industry experience in oligonucleotide manufacturing process development and/or manufacturing
• Experience in GMP and ISO manufacturing environment
• Experience in a manufacturing environment working with standard production control tools – ERP, LIMS, inventory control, work orders, etc.
• Experience with Non Conformance Reports, Deviations, Corrective and Preventive Actions
• Strong computer skills - Excel, Word, and Google Suite
• Experience working in a BSL-2 and cleanroom laboratory environment
• Must be able to stand for long periods of time while performing duties
• Must be able to work safely with chemicals and hazardous materials
• Must be able to lift up to 25 lbs and move between multiple lab facilities
• Proven ability to write SOPs and train others to successfully perform the work.

Preferred Experience and Qualifications:

• Desire to be part of a rapidly evolving organization with the ability to work in a fast-paced and quickly changing environment
• Strong organizational, collaboration, and written and oral communication skills
• Strong analytical skills with the ability to use statistical tools (e.g. JMP) to summarize data
• Ability to multitask and work in a dynamic environment while maintaining efficiency
• Capable of working collaboratively in a team environment

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