Band

Level 5

Job Description Summary

In this role, you will contribute to defining the biomarker strategies and plans for a set of programs/projects, defined by asset or by indication, from early to later stage clinical development. By collaborating with global biomarker teams and line functions, you will oversee the integration into clinical protocols, lead the review and discussions at the different teams and boards, and lead a matrixed biomarker team of scientific experts to build on the biomarker strategies and plans. You will also build external collaborations with academia or clinical sites in China to advance the knowledge around translational sciences and biomarker solutions focused on diseases, indications or pathways. You will be responsible for driving/supporting clinical translational research effort in China, encompassing translational research strategy development, capability enhancement and project leadership, and translating the preclinical discovery efforts into a clinical fit for purpose plan.

Job Description

Key responsibilities:

• Contribute to China translational research strategy development based on global and China pipeline needs and clinical translational landscape in China.

• Identify external institutions and clinical resources with collaboration opportunities, including patient cohorts, biobanks, clinical databases, disease models and innovative proposals from academic researchers and clinical investigators.

• Represent Biomedical Research/Translational Medicine research expertise in scientific communication with academic institutions for establishing and maintaining strategic partnership with local investigators around biomarkers and translational research.

• Initiate translational research collaboration projects in China, solicit and secure adequate support for collaboration, and provide scientific leadership in China translational research projects, e.g., research collaboration.

• Acts as BMD strategic and scientific leader in China at project or collaboration level to lead or contribute to biomarker strategies and plans with the various local and global team members.

• Develops deep understanding of the translational biomarkers for a project/program (and associated clinical studies), focused on compound, disease, target, and pathway biology.

• Support health authorities’ interactions around biomarkers and translational research.

• Ensures alignment and connectivity with other Biomarker Leads, Therapeutic Area Leads and Heads across assets, indications, and therapeutic areas.

• Partner with Biomarker Study Experts (BSE) and BMD Line Function Subject Matter Experts (SMEs) on the study strategic planning, and biomarker implementation.

• Is responsible for the contextualization and interpretation of the biomarker data including CSR review.

• Cooperates closely with Therapeutic Area Biomarker Head (TABH) or Therapeutic Area Biomarker Lead (TABL) as well as BMD Line Functions to enable the development of project/study level biomarker strategy and plans, implementation, contextualizing, and interpretation.

• Is an enterprise partner and strategic leader in the matrix environment, able to integrate and represent projects in the internal/external scientific discussions and initiatives, including collaboration with China Development and Commercial.

Essential requirements:

• PhD, MD, or MD/PhD degree with a minimum of 5 years’ experience in drug discovery or development.

• Good understanding of biology and translational research that can be applied to questions of patient’s selection, enrichment, dose selection, efficacy and response, disease progression, mechanism of actions, among others.

• Scientific excellence supported by academic and/or industry career track, and/or high -quality publications; clinical and/or biological expertise.

• In-depth knowledge of the medical and healthcare ecosystem in China.

• Highly self-motivated and collaborative, with a demonstrated ability to work effectively in diverse teams

• Fluent in oral and written English

Desirable requirements:

• Significant relevant experience after your MD/PhD/postdoc including drug development, clinical research/development, or translational research.

• Track record of contributions to clinical programs and studies in pharma industry (or biotech) is strongly preferred.

• Proven success in leading and partnering in multidisciplinary matrix teams across Pharma/biotech, or academic institutions.

• Creative and innovative leadership, experience in balancing big picture thinking with detailed analyses and operational aspects.

• Well-developed interpersonal and leadership skills with strong presence and ability to influence and navigate large organizational structures as well connect and network with external investigators.

Skills Desired

Analytical Skill, Analytical Skill, Analytical Thinking, Chemical Biology, Chemistry, Clinical Research, Clinical Trials, Collaboration, Communication Skills, Curious Mindset, Data, Data Analysis, Decision Making, Design Of Experiments, Detail-Oriented, Drug Development, Drug Discovery, Ethics, Gene Therapy- Leadership, Influence, Laboratory, Lifesciences, Machine Learning (ML), Medical Research, Mentorship {+ 11 more}