Sr. Project Manager, Engineering
Constellation Pharmaceuticals
Operations
Durham, NC, USA
Band
Level 4
Job Description Summary
Bring your experience, leadership, and strategic mindset to a role where your work directly enables the delivery of innovative therapies to patients around the world. As a Sr. Project Manager, Engineering at Novartis, you will lead a complex portfolio of capital projects within a regulated manufacturing environment, guiding teams through ambiguity and technical challenges with confidence. You will serve as a trusted partner to site leadership, drive decisions that shape long‑term manufacturing strategy, and champion operational excellence while balancing cost, quality, and schedule. This role offers the opportunity to influence at scale, mentor teams, and leave a lasting footprint across the site’s capital portfolio.
Job Description
Key Responsibilities:
- Lead multiple capital projects from initiation through close‑out, ensuring delivery on time, within budget, and to quality standards
- Act as primary client contact, proactively managing stakeholder expectations and maintaining strong working relationships
- Manage project scope, schedule, and budget changes with clear impact assessments and documented approvals
- Oversee contractors and internal teams, ensuring safe, compliant, and effective project execution
- Resolve project issues, risks, and resource constraints in partnership with site leadership
- Prepare and manage project budgets, forecasts, and funding documentation
- Develop project objectives aligned with business plans and user requirements
- Coordinate planning and scheduling across project teams and manufacturing operations
- Communicate project performance, risks, and mitigation plans to site and senior leadership
- Drive operational excellence by capturing lessons learned and supporting continuous improvement initiatives
Essential Requirements:
- Bachelor’s degree in Chemical, Electrical, or Mechanical Engineering, or a related technical field, or equivalent experience
- Nine years of experience supporting pharmaceutical or biopharmaceutical manufacturing operations in regulated environments
- Demonstrated experience leading FDA‑regulated and GMP‑compliant projects within highly regulated facilities
- Strong knowledge of FDA regulations and Good Manufacturing Practice systems
- Experience delivering capital improvement projects, including process and production layout development
- Experience managing Good Manufacturing Practice construction activities in brownfield and renovation environments
- Applied knowledge of Quality by Design, Six Sigma, and operational excellence methodologies
- Excellent written and verbal communication skills, including strong technical writing capabilities
Novartis Compensation and Benefit Summary:
The salary for this position is expected to range between $108,500 and $201,500 annually
The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.
Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.
US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.
#LI-Onsite
EEO Statement:
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
Accessibility and reasonable accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to tas.nacomms@novartis.com call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
https://www.novartis.com/careers/careers-research/notice-all-applicants-us-job-openings
Salary Range
$108,500.00 - $201,500.00
Skills Desired
Business Continuity, Cost Management, Data Analytics and Digital, Decision Making, Engineering Operations Management, Engineering Technical Expertise, GDP Knowledge, gmp knowledge, HSE Knowledge, Manufacturing Process (Production), Operational Excellence, Problem Solving, Project Management, Quality Compliance, Resilience and Risk Management, Resource Planning and Forecasting, Risk Management, Stakeholder Management, Vendor Management