Encoded Therapeutics is a clinical-stage genetic medicines company developing potentially disease-modifying therapies to improve the lives of people with severe CNS disorders. Our proprietary vector engineering approach combines novel regulatory elements and payloads with AAV vectors to unlock innovative solutions for debilitating, intractable CNS conditions. At the forefront is our flagship clinical program, ETX101 for Dravet syndrome, which targets the underlying cause of the disorder to enable highly selective upregulation of SCN1A for potentially long-lasting benefit. In parallel, we are advancing a pipeline of potentially best-in-class programs to address significant unmet needs across both monogenic and prevalent CNS conditions. For more information, please visit www.encoded.com.

Encoded is seeking a Senior Research Associate, Analytical Development/Mass Spectrometry. Tthis position is based at Encoded’s corporate office in South San Francisco.

• Design and perform protein characterizations including intact MS, Peptide mapping and HCP analysis by proteomics
• Develop and optimize protein chemistry and biophysical characterization methods including HPLC (SEC, IEX, Affinity, RPLC) and CE
• Collaborate with cross-functional teams to support analytical development, process development and comparability studies.
• Operate under Good Documentation Practice for efficient data management and retrieval.
• Record experimental procedure and results accurately in laboratory notebooks
• Work on multiple projects to meet departmental and organization goals