About Moonlight Bio

Moonlight Bio is a Seattle-based, preclinical stage biotech company pioneering the development of cutting-edge cell therapies for the treatment of cancer. Our team is comprised of highly collaborative individuals who are passionate about designing innovative technologies and drug candidates with the potential to transform the lives of cancer patients. Engaging across the full landscape of drug development, Moonlight’s team members are pursuing opportunities in discovery research, component design and screening, preclinical modeling, process and analytical development, translational studies, and partnerships necessary to enable and advance our core technologies. We believe in cultivating a balanced work-life environment that values diversity and inclusivity.

Roles & Responsibilities

We are seeking a highly motivated and skilled Scientist, with a strong background in T cell engineering, to join our team. This position is primarily a lab-based role, working on-site in our office and laboratory in Seattle’s Eastlake neighborhood, and will be reporting to the Director of Research & Development. This role will develop research strategies that span the design and assessment of innovative potency enhanced CAR or TCR based T cell therapies. It will involve discovering and assessing diverse potency enhancement components and strategies that support product conceptualization and development. The ideal candidate will be a scientist with experience in the cell and gene therapy field, who has demonstrated scientific excellence, a strong sense of curiosity, and a proven capacity for working collaboratively with a team science mindset to tackle the myriad challenges that come with developing cell therapies.

A typical day may involve the following activities

• Designing and assessing novel CAR and TCR architectures
• Developing in vitro and/or in vivo screening platforms to enable discovery and assessment of potency enhancement strategies
• Compiling, analyzing, and presenting data to various audiences, including executive leadership, advisory boards, founders, and external collaborators.
• Serving on cross-functional project teams and actively engaging in team discussions

We are looking for candidates who possess the following qualifications

• PhD degree in molecular biology, protein engineering, genetics, immunology, or related discipline with 2+ years of post-graduate experience
• Established knowledge and technical proficiency in engineered T cell biology and related in vitro and in vivo characterization and functional assessments, with preferential experience in utilizing 1) various protein modeling tools (e.g., AlphaFold, PyMol) for protein design; 2) gene editing tools (e.g., Cas nucleases, prime/base editors) for T cell engineering; 3) in vitro and/or in vivo screening platforms for functional assessment of engineered T cells
• Demonstrated track record of producing high quality scientific results as an individual contributor
• Excellent organization and communication skills (written and oral) to meet deadlines and balance time and effort across multiple workstreams
• Enthusiasm for creative, solution-oriented thinking and working collaboratively in a team environment

What You Should Know

Full Time Employees (and their eligible dependents) may enroll in medical, dental, vision, life insurance, and disability plan. In addition, employees may receive stock option grants to be outlined in their offer of employment. Moonlight employees enjoy flexible time off (FTO) and sick leave, which complies with local requirements, and twelve paid holidays throughout the calendar year. Moonlight also offers paid parental leave policy to all regular full-time employees.

At Moonlight Bio, we are committed to growing and nurturing a diverse team, providing equal employment opportunities to all employees and applicants without regard to characteristics and statuses protected under applicable federal, state, and local laws.

Our employee benefits include FTO, subsidized on-site parking, medical, dental, and vision plans and other benefits from your first day of employment.

Join us at Moonlight Bio and contribute to groundbreaking research that has the potential to revolutionize cancer treatment! With dedication to professional development, you’ll have the opportunity to make a meaningful impact on patients’ lives while advancing your career in the dynamic field of cell therapy.

Please apply directly within LinkedIn or submit your resume/CV and cover letter to careers@moonlightbio.us