Senior Associate Scientist I/Principal Associate Scientist, Preclinical Pharmacology
Kelonia Therapeutics
Boston, MA, USA
Posted on Mar 24, 2026
At Kelonia Therapeutics, our ambitions are bold: to dramatically expand the benefit and reach of genetic medicines. Our goal is to change what’s possible for genetic medicine by building the capabilities, experience, and commitment to bring life-saving medicine to every patient in need. We are a human-first company, driven by a mission to develop transformative genetic medicines for patients and their loved ones.
We have brought together pioneers in cell and gene therapy, guided by extraordinary scientific founders and a team committed to turning breakthrough science into real-world impact. As we grow, we are building a culture that values rigor, collaboration, and care for one another.
What You'll Do:
- Plan and execute in vivo pharmacology studies using Kelonia’s proprietary LVV gene delivery technology in close collaboration with research scientists and cross-functional partners.
- Contribute to the design, execution, and optimization of translational and platform mouse studies, including pilot, proof-of-concept, and mechanism-focused experiments.
- Perform animal handling and in vivo procedures, including compound administration, blood collection, IVIS imaging, necropsy, and tissue harvest.
- Process tissues and samples ex vivo to support downstream analysis and help establish efficient workflows for sample collection and handoff.
- Analyze, interpret, and clearly document study data using Excel, GraphPad Prism, and electronic lab notebooks; ensure high-quality, organized, and inspection-ready records.
- Compile, summarize, and present data to cross-functional teams, highlighting key findings, experimental observations, and next-step recommendations.
- Identify experimental issues, troubleshoot study execution challenges, and propose practical solutions to improve quality, reproducibility, and throughput.
- Support onboarding and informal training of junior team members on core in vivo techniques, workflow execution, and documentation best practices.
What You'll Bring:
- BS or MS degree in Biology, Pharmacology, or a related scientific discipline with typically 4+ years of relevant academic and/or industry experience; level may be adjusted based on overall background and skillset.
- Must have hands-on experience conducting rodent in vivo studies, including IVIS imaging, caliper measurement of subcutaneous tumors, anesthesia, blood collection, euthanasia, necropsy and tissue collection, and administration via multiple dosing routes (IV, IP, SC, and intratumoral).
- Demonstrated ability to execute studies with a high degree of independence while knowing when to escalate questions or risks.
- Experience analyzing and interpreting experimental data, drawing clear conclusions, and communicating results effectively to scientific stakeholders.
- Strong attention to detail and a consistent track record of clear, thorough documentation and adherence to written procedures.
- Ability to balance multiple priorities, adapt to changing project needs, and deliver high-quality work in a dynamic research setting.
- Collaborative mindset with strong communication skills and the ability to work effectively across a multidisciplinary team.
- Experience contributing to troubleshooting, workflow improvement, and experimental optimization is strongly preferred.
At Kelonia, we’re serious about balance and growth. We offer Flexible Time Off and flexible scheduling aligned with team objectives, a competitive benefits package (health, commuter, and more), and on-site perks including free parking, a state-of-the-art gym, and a food hall, all within a collaborative, inclusive team that invests in your development.
Kelonia Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.
Kelonia does not accept unsolicited resumes from any source other than directly from candidates.